Cape Girardeau Vacations

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Your Cape Girardeau Vacation

Food, history, entertainment and more … There's so much to immerse yourself in with a Cape Girardeau vacation package. And with the ability to easily customize your city break, it's guaranteed to be one that's memorable. If sightseeing is on the agenda during your trip to Cape Girardeau, swing by major attractions like Isle Casino Cape Girardeau, Cape Rock Park and Cape Girardeau Conservation Nature Center. Expedia will help you escape your routine. Tailor your vacation to Cape Girardeau to suit your travel style, whatever that may be.

Discover the most popular places to visit in Cape Girardeau

Southeast Missouri State University

Take a campus tour or just explore the area of Southeast Missouri State University, during your trip to Cape Girardeau. While in this family-friendly area, you can savor the top-notch restaurants.

Southeast Missouri State University

Isle Casino Cape Girardeau

Why not roll the dice with a visit to Isle Casino Cape Girardeau during your travels in Cape Girardeau? While in this family-friendly area, you can savor the top-notch restaurants.

Isle Casino Cape Girardeau

Riverfront Bridge Park

Riverfront Bridge Park is just one of the places to see in Cape Girardeau, so why not enjoy the other things to explore during your travels? While in this family-friendly area, you can savor the top-notch restaurants.

Riverfront Bridge Park

Cape Girardeau Hotel Deals

The Riverview

The Riverview

2 out of 5
777 Main St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $132 total per night from Aug 17 to Aug 18
$132 total
Aug 17 - Aug 18
Total includes taxes and fees
9.2/10 Wonderful! (374 reviews)
Definitely recommend.
"This is my 2nd stay and each time has been flawless. Parking is convenient, lobby is clean and check in is a breeze. The rooms are spacious, clean and comfortable. I don't stay here for the casino life but that entertainment option is also very convenient. The availability of having Starbucks downstairs ..."

Reviewed on Aug 9, 2025

The Riverview
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3 out of 5
3351 Percy Drive, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$102 nightly
The price is $115 total per night from Aug 17 to Aug 18
$115 total
Aug 17 - Aug 18
Total includes taxes and fees
9.4/10 Exceptional! (1,005 reviews)
"I always like Drurys because you can count on the breakfast and pool and clean rooms."

Reviewed on Aug 7, 2025

Drury Plaza Hotel Cape Girardeau Conference Center
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 out of 5
3248 William St, Cape Girardeau, MO
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Aug 17 to Aug 18
$79 total
Aug 17 - Aug 18
Total includes taxes and fees
8.8/10 Excellent! (1,000 reviews)
Great Hotel for the Price
"My family was driving back from vacation and needed a last minute place to rest for the night. It was overall a great stay for the price. They had a portable crib for my toddler along with popcorn in the lobby. The staff were friendly and accommodating. Lots of choices for nearby restaurants."

Reviewed on Aug 3, 2025

Pear Tree Inn Cape Girardeau Near the Medical Center
See all 151 properties in Cape Girardeau
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Frequently asked questions

How much does a Cape Girardeau vacation package cost?
Offering excellent value package deals on Expedia, you'll be pleasantly surprised at how much a vacation to Cape Girardeau costs! Expedia's packages make travel planning easier and save you more.
What are the cheapest months to go to Cape Girardeau?
If you're looking to score a cheap Cape Girardeau vacation package, consider traveling in March, September and November. You're likely to find lower prices on hotels and airfares during these months — perfect for a budget-friendly getaway.
How many days is enough for Cape Girardeau?
With a well-planned schedule, you can easily hit the main Cape Girardeau sights in a handful of days. But if you'd like to discover lesser-known spots or take day trips, think about booking your Cape Girardeau vacation for longer.
Is it worth booking a vacation package to Cape Girardeau?
Cape Girardeau has everything you need for the perfect break — history, culture and family-friendly attractions are just the start. Whether you want to visit sights such as Cape Rock Park and Fort D Historic Site, or venture off the beaten track, you'll have plenty to experience on your Cape Girardeau vacation.
How to find the best Cape Girardeau package deals?
Start your search for a Cape Girardeau package deal by entering your preferred travel dates and destination under our "Packages" tab. Then select some filters, like "Popular locations" and "Property type," to fine-tune the results to your exact style. You can also sort by "Package discount" and discover offers that come with unbeatable savings. If you don't find the perfect Cape Girardeau package deal right away, simply change your dates and search again. Bear in mind that deals are only available for a limited time, so book early and get your Cape Girardeau adventure underway.
Is it cheaper to book a Cape Girardeau vacation as a package?
You can enjoy significant savings on your Cape Girardeau retreat by booking a tailored vacation package. Click on the "Package" heading, then enter your destination and travel dates to view the best flight and hotel prices. Bundling can save travelers hundreds of dollars. Consider adding a car rental and you may land a better deal.
When to book a vacation package to Cape Girardeau?
If you're planning a spontaneous Cape Girardeau trip, browse our last-minute deals that can be booked up to one week before you go. Prefer not to wait until the last minute? You can land awesome deals on your flights and hotels by booking well in advance.
Does Expedia offer Book Now, Pay Later Cape Girardeau vacation packages?
If you're like us, you love exploring new places but don't love the price tag that can come with it. That's why we've created Book Now, Pay Later vacations. With help from online lender Affirm, you can break down the total cost of your Cape Girardeau trip over 3, 6 or 12 months. There are also no hidden or late payment fees, so you can secure great vacation packages with payment plans as soon as you see them.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.